Skip to Content
Home > Patients & Visitors > Health Library > Mononucleosis Complications
View Additional Content In This Section
Most people recover from mononucleosis (mono) without any
complications. But there are many possible complications of mono. These
include:1, 2, 3
Other complications of mono can occur but are very rare.
While it is not a complication specific to mono, a serious
disease known as
Reye syndrome can develop if you give aspirin to
a person younger than 20 to treat symptoms of mono.
Aspirin should not be used to treat symptoms of mono. Other medicines, such as acetaminophen (for example, Tylenol) or ibuprofen (for example, Advil) can help relieve fever and pain caused by
mono. Follow all instructions on the label.
Even if you have a complication of mono, it is likely
that you will recover completely.
Johannsen EC, Kaye KM (2010). Epstein-Barr virus
(infectious mononucleosis, Epstein-Barr virus-associated malignant diseases, and other diseases). In GL Mandell et al., eds., Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th ed., vol. 2, pp. 1989–2010. Philadelphia:
Churchill Livingstone Elsevier.
American Public Health Association
(2008). Mononucleosis, infectious. In DL Heymann, ed.,
Control of Communicable Diseases Manual, 19th
ed., pp. 428–430. Washington, DC: American Public Health
Levin MJ, Weinberg A (2011). Infectious
mononucleosis (Epstein-Barr virus) section of Infections: Viral and rickettsial. In WW Hay Jr et al., eds.,
Current Diagnosis and Treatment: Pediatrics, 20th ed.,
pp. 1131–1133. New York: McGraw Hill Medical.
July 28, 2011
E. Gregory Thompson, MD - Internal Medicine & W. David Colby IV, MSc, MD, FRCPC - Infectious Disease
How this information was developed to help you make better health decisions.
To learn more visit Healthwise.org
© 1995-2013 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Request an appointment online>>
2650 Siskiyou Blvd., Medford, OR 97504