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Omega-3 fatty acids are found in marine or plant sources,
such as fish oil and flaxseed oil. Preliminary studies suggest that people with
bipolar disorder who take omega-3 fatty acids have a
significantly longer period in which their mood is stable with no episodes of
depression or mania (remission).1
are few, if any, negative side effects of taking omega-3 fatty acids. Loose
stools were reported most often. Researchers think that omega-3 fatty acids may
block signals in the central nervous system that trigger depression and mania.
But more research needs to be conducted before there is sufficient evidence
that omega-3 fatty acids improve the course of bipolar disorder.2
Lin PY, Su KP (2007). A meta-analytic review of
double-blind, placebo-controlled trials for antidepressant efficacy of omega-3
fatty acids. Journal of Clinical Psychiatry, 68(7):
Montgomery P, Richardson AJ (2009). Omega-3 fatty acids for bipolar disorder. Cochrane Database of Systematic Reviews (1).
March 1, 2012
Patrice Burgess, MD - Family Medicine & Lisa S. Weinstock, MD - Psychiatry
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